CT gene modulate differential expression of chitinase gene under variant habitats in Vibrio cholerae
نویسندگان
چکیده
منابع مشابه
TolC affects virulence gene expression in Vibrio cholerae.
A Vibrio cholerae tolC mutant showed increased toxT expression in M9 medium, but not in the presence of four amino acids that induce cholera toxin production, and in LB with high osmolarity but not high pH or temperature. TolC did not affect expression of other regulatory genes in the ToxR regulon.
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The production of virulence factors including cholera toxin and the toxin-coregulated pilus in the human pathogen Vibrio cholerae is strongly influenced by environmental conditions. The well-characterized ToxR signal transduction cascade is responsible for sensing and integrating the environmental information and controlling the virulence regulon. We show here that, in addition to the known com...
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We previously found that inhibition of the TCA cycle, either through mutations or chemical inhibition, increased toxT transcription in Vibrio cholerae. In this study, we found that the addition of malonate, an inhibitor of succinate dehydrogenase (SDH), decreased toxT transcription in V. cholerae, an observation inconsistent with the previous pattern observed. Unlike another SDH inhibitor, 2-th...
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ژورنال
عنوان ژورنال: Asian Pacific Journal of Tropical Disease
سال: 2013
ISSN: 2222-1808
DOI: 10.1016/s2222-1808(13)60005-5